Bulletin of Rehabilitation Medicine Bulletin of Rehabilitation Medicine Вестник восстановительной медицины 2078-1962 2713-2625 68970 10.38025/2078-1962-2022-21-5-42-49 Технологии восстановительной медицины и медицинской реабилитации Rehabilitation Medicine and Medical Rehabilitation Technologies Технологии восстановительной медицины и медицинской реабилитации The Effect of Lifestyle Correction Based on Body Composition Intervention on Clinical Efficacy: a Prospective Comparative Randomized Study of Polycystic Ovary Syndrome Patients Влияние изменения образа жизни на основе коррекции состава тела на клиническую эффективность: проспективное сравнительное рандомизированное исследование пациентов с синдромом поликистозных яичников Чжан Синь-Юань. Xin-Yuan. Чжан Zhang Xin-Yuan. Фу Линг-Линг. Ling-Ling. Фу Fu Ling-Ling. Сонг Ке. Ke. Сонг Song Ke. Хэ Тинг-Тинг. Ting-Ting. Хэ He Ting-Ting. Ян Цзин. Jing. Ян Yang Jing. Чан Цзюнь. Jun. Чан Chang Jun. Су Ли. Мэн. Meng. Su Li. Ли Цзе. Jie. Ли Li Jie. Яо Лэй. Lei. Яо Yao Lei. Чжан Янь. Yan. Чжан Zhang Yan. Лю Цзян-Лин. Jiang-Ling. Лю Liu Jiang-Ling. Первая народная больница Урумчи, Синьцзян, Китай ru Первая народная больница Урумчи, Синьцзян, Китай ru 25 10 2022 25 10 2022 21 5 42 49 12 10 2022 20 10 2022 https://nmicrk.editorum.ru/en/nauka/article/68970/view

ВВЕДЕНИЕ. Синдром поликистозных яичников – это эндокринно-метаболическое заболевание, показатели по распространённости которого постоянно растут. Он характеризуется различными клиническими составляющими, основными из которых являются избыток андрогенов, олиго-ановуляторное бесплодие, поликистоз яичников, инсулинорезистентность (ИР) и кардиометаболические изменения. ЦЕЛЬ. Изучить клинический эффект корректировки образа жизни на основе состава тела у пациенток с синдромом поликистозных яичников. МАТЕРИАЛ И МЕТОДЫ. В период с ноября 2020 года по июль 2021 года 91 пациентка с диагнозом синдрома полкистозных яичников в Первой народной больнице Урумчи была проспективно отобрана и разделена на контрольную (46 человек) и экспериментальную (45 человек) группы в соответствии с методом случайных чисел. Пациентки контрольной группы принимали таблетки дроспиренона и этинилэстрадиола (II), а пациентки экспериментальной группы – таблетки дроспиренона и этинилэстрадиола (II) и проходили корректировку образа жизни в зависимости от состава тела. Изменения индексов до и после 3 месяцев лечения сравнивались между двумя группами. РЕЗУЛЬТАТЫ. Показатели пациентов с синдромом поликистозных яичников в двух группах после лечения (за исключением 1 базальной скорости метаболизма и веса мышц, 2. гонадотропный гормон и 3. ЛПВП) снизились, причем снижение в экспериментальной группе было более значительным (P < 0,05). У пациенток в экспериментальной группе значительно повысился уровень спонтанной овуляции и беременности. ЗАКЛЮЧЕНИЕ. У пациенток с синдромом поликистоза яичников комбинация таблеток Дроспиренона и Этинилэстрадиола (II) и изменения образа жизни на основе на основе коррекции состава тела может значительно улучшить репродуктивный гормон, метаболизм глюкозы и резистентность к инсулину, что благоприятно для спонтанной овуляции и беременности, а также снизить вес пациенток.

AIM. To study the clinical effect of body composition-based lifestyle intervention in patients with polycystic ovary syndrome (PCOS). MATERIAL AND METHODS. In the period of November, 2020 – July, 2021, 91 patients diagnosed with PCOS in the First People's Hospital of Urumqi were prospectively selected and divided into a control group (46 cases) and an experimental group (45 cases) according to random number method. The patients in the control group were treated with Drospirenone and Ethinylestradiol tablets (II), while the patients in the experimental group were treated with Drospirenone and Ethinylestradiol tablets (II) and lifestyle adjustment based on body composition. The changes of the indices before and after 3 months of treatment were compared between the two groups. RESULTS. The indices of PCOS patients in the two groups after treatment (except 1 basal metabolic rate and muscle weight, 2. FSH and 3. HDL) were decreased, and the decrease in the experimental group was more significant (P < 0.05). Patients in the experimental group had significantly increased spontaneous ovulation and pregnancy rate / Conducive to ovulation and pregnancy. CONCLUSION. In PCOS patients, the combination of Drospirenone and Ethinylestradiol tablets (II) and lifestyle intervention based on human body components can improve reproductive hormone, glucose metabolism and insulin resistance more effectively, which is beneficial to spontaneous ovulation and pregnancy, and reduce the weight of patients.

 состав тела образ жизни синдром поликистозных яичников антимюллеров гормон инсулинорезистентность body composition life style polycystic ovary syndrome Anti-Mullerian hormone Insulin resistance

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