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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Bulletin of Rehabilitation Medicine</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Bulletin of Rehabilitation Medicine</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Вестник восстановительной медицины</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2078-1962</issn>
   <issn publication-format="online">2713-2625</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">68960</article-id>
   <article-id pub-id-type="doi">10.38025/2078-1962-2022-21-2-99-107</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Технологии восстановительной медицины и медицинской реабилитации</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>Rehabilitation Medicine and Medical Rehabilitation Technologies</subject>
    </subj-group>
    <subj-group>
     <subject>Технологии восстановительной медицины и медицинской реабилитации</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">The Sustained Physical Activity Role in Overcoming Fatigue in Patients with Rheumatoid Arthritis</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Роль устойчивой физической активности в преодолении усталости у пациентов с ревматоидным артритом</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0686-4067</contrib-id>
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Александров</surname>
       <given-names>А. В.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Aleksandrov.</surname>
       <given-names>Andrey V.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9047-4311</contrib-id>
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Никитин</surname>
       <given-names>М. В.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Nikitin.</surname>
       <given-names>Mikhail V.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4500-7172</contrib-id>
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Александров</surname>
       <given-names>В. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Aleksandrov.</surname>
       <given-names>Vladislav A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0438-8554</contrib-id>
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Шилова</surname>
       <given-names>Л. Н.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Shilova.</surname>
       <given-names>Ludmila N.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8124-4239</contrib-id>
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Александрова</surname>
       <given-names>Н. В.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Aleksandrova.</surname>
       <given-names>Ninel V.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3898-7667</contrib-id>
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Зборовская</surname>
       <given-names>И. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Zborovskaya.</surname>
       <given-names>Irina A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Научно-исследовательский институт клинической и экспериментальной ревматологии им. А.Б. Зборовского, Волгоград, Россия</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">Научно-исследовательский институт клинической и экспериментальной ревматологии им. А.Б. Зборовского, Волгоград, Россия</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Волгоградский государственный медицинский университет Минздрава России, Волгоград, Россия</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">Волгоградский государственный медицинский университет Минздрава России, Волгоград, Россия</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Национальный медицинский исследовательский центр реабилитации и курортологии Минздрава России, Москва, Россия</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">Национальный медицинский исследовательский центр реабилитации и курортологии Минздрава России, Москва, Россия</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2022-04-25T14:01:20+03:00">
    <day>25</day>
    <month>04</month>
    <year>2022</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2022-04-25T14:01:20+03:00">
    <day>25</day>
    <month>04</month>
    <year>2022</year>
   </pub-date>
   <volume>21</volume>
   <issue>2</issue>
   <fpage>99</fpage>
   <lpage>107</lpage>
   <history>
    <date date-type="received" iso-8601-date="2022-04-12T14:01:20+03:00">
     <day>12</day>
     <month>04</month>
     <year>2022</year>
    </date>
    <date date-type="accepted" iso-8601-date="2022-04-20T14:01:20+03:00">
     <day>20</day>
     <month>04</month>
     <year>2022</year>
    </date>
   </history>
   <self-uri xlink:href="https://nmicrk.editorum.ru/en/nauka/article/68960/view">https://nmicrk.editorum.ru/en/nauka/article/68960/view</self-uri>
   <abstract xml:lang="ru">
    <p>Недостаток знаний о причинах усталости часто ведет к игнорированию данного симптома при ревматоидном артрите (РА). При активном использовании нефармакологических стратегий лечения можно существенно уменьшить тяжесть усталости у пациентов с РА.&#13;
Цель. Оценить эффективность аэробных упражнений (ходьба) для снижения усталости у больных РА при длительном наблюдении.&#13;
Материал и методы. В исследовании приняли участие 102 пациента с РА (женщины 100%; средний возраст 54,38±11,3 года; длительность заболевания 9,5 [5; 15] лет; активность по DAS28-СОЭ – 2,85 [2,32; 3,06] баллов; усталость по шкале VAS ≥50), которые завершили этап санаторного лечения в полном объеме (21 день) и представили данные об аэробной физической нагрузке (количество шагов в день) и оценке усталости по Британской шкале усталости при ревматоидном артрите – числовая шкала оценки (BRAF-NRS V2). По уровню физической активности больные РА разделились на две группы: группа I (n=53) с малоподвижным образом жизни (менее 5–6 тысяч шагов/день) и группа II (n=49) с рекомендуемым (подвижным) образом жизни (более 7–8 тысяч шагов/день). Через 2 месяца после возвращения из санатория была проведена оценка приверженности больных РА физическим нагрузкам, а также зафиксирована динамика показателей усталости по BRAF-NRS. Результаты и обсуждение. В заключительном опросе согласились участвовать 76 человек (74,5%): 32 пациента из I группы и 44 пациента из II группы. Приверженность к ежедневным аэробным нагрузкам (более 5 тысяч шагов в день) в I группе сохранили 34% участников, во II группе – 59% (p=0,033). Большинство респондентов (51,3%) снизили уровень физической активности и после возвращения из санатория существенно сократили время на аэробные упражнения, ссылаясь на нехватку стимулов и времени. 47% пациентов из I группы (15/32) чувствовали себя в состоянии уделять большее внимание физической активности, однако только 25% подтвердили твердую уверенность, что они станут отводить аэробным физическим упражнениям не менее 30 минут 5 раз в неделю в ближайшие три месяца. Во II группе о сохранении и даже увеличении подобного объема физических нагрузок заявило в два раза больше (48%) пациентов (p=0,044), подтвердив эффективность индивидуальных программ физической активности, сформированных во время санаторно-курортного лечения и интегрированных затем в повседневную жизнь. По прошествии двух месяцев после возвращения из санатория пациенты из II группы показали более низкие показатели усталости по всем шкалам BRAF-NRS: по NRS-степень тяжести (р=0,04), по NRS-эффект (р=0,005) и по NRS-преодоление (р=0,034). При проведении дисперсионного анализа было отмечено снижение уровня усталости в среднесрочной (до 2 месяцев) перспективе независимо от уровня физической активности пациентов, но у больных РА, приверженных активному образу жизни и регулярным аэробным физическим нагрузкам (группа II), положительные изменения были наиболее выражены (p&lt;0,001).&#13;
Заключение. Положительный эффект аэробных упражнений (ходьба) на снижение утомляемости значительно нивелируется даже в среднесрочной перспективе, если пациенты не продолжают вести активный образ жизни. По завершению санаторно-курортного этапа лечения (с подбором оптимальной дозы и частоты физических нагрузок) следует дополнительно побуждать больных РА к ежедневным аэробным упражнениям и оказывать поддержку в продолжении программ реабилитации по месту жительства с целью достижения лучшего эффекта в долгосрочной перспективе.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Lack of knowledge about the causes of fatigue often leads to ignoring this symptom in rheumatoid arthritis (RA). The severity of fatigue in patients with RA can be significantly reduced by actively using non-pharmacological treatment strategies. &#13;
Aim. To evaluate the effectiveness of aerobic exercise (walking) to reduce fatigue in RA patients during long-term follow-up. Material and methods. The study involved 102 patients with RA (women 100%; average age 54.38 ± 11.3 years; disease duration 9.5[5;15] years; DAS28-ESR activity 2.85[2.32;3.06] points; fatigue on the VAS scale ≥50), who completed the stage of sanatorium treatment in full (21 days) and provided data on aerobic physical activity (steps quantity per day) and fatigue scores on the British Rheumatoid Arthritis Fatigue Scale – Numerical Rating Scale (BRAF-NRS V2). RA patients were divided into two groups according to their level of physical activity: group I (n=53) with a sedentary lifestyle (less than 5–6 thousand steps/day) and group II (n=49) with a recommended (mobile) lifestyle (more than 7–8 thousand steps/day). Assessment of RA patients’ adherence to physical activity was carried out 2 months after return from the sanatorium, and the dynamics of BRAF-NRS fatigue indexes were recorded. Results and discussion. Seventy-six people (74.5%) agreed to participate in the final survey: 32 patients from a group I and 44 patients from a group II. Commitment to daily aerobic activity (more than 5,000 steps per day) was maintained by 34% of participants in the group I and 59% in the group II (p=0.033). The majority of respondents (51.3%) decreased the physical activity level and significantly reduced the time for aerobic exercise after returning from the sanatorium, citing a lack of incentives and time. 47% of the group I patients (15/32) felt able to devote more attention to physical activity, but only 25% confirmed a strong belief that they would dedicate at least 30 minutes to aerobic exercise 5 times a week over the next three months. In the group II, 48% of patients (p=0.044) reported maintaining or even increasing the corresponding physical activity level, confirming the effectiveness of individual physical activity programs formed during the sanatorium treatment and then integrated into daily life. Two months after returning from the sanatorium, group II patients showed lower fatigue scores on all BRAF-NRS scales: NRS-severity (p=0.04), NRS-effect (p=0.005), and NRS-overcoming (p=0.034). The analysis of variance revealed a decrease in the level of fatigue in the medium term (up to 2 months) regardless of the level of physical activity of the patients, but in RA patients committed to an active lifestyle and regular aerobic physical activity (group II), the positive changes were most pronounced (p&lt;0.001).&#13;
Conclusion. The positive effect of aerobic exercise (walking) on reducing fatigue is significantly negated even in the med-term, if patients do not continue to lead an active lifestyle. After completion of the sanatorium stage of treatment (with selection of optimal dose and frequency of physical activity), RA patients should be further encouraged to do daily aerobic exercises and be supported to continue rehabilitation programs in the community in order to achieve a better effect in the long term.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>ревматоидный артрит</kwd>
    <kwd>усталость</kwd>
    <kwd>аэробные физические упражнения</kwd>
    <kwd>санаторно-курортное лечение</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>rheumatoid arthritis; fatigue; aerobic exercises; health resort treatment</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
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